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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CAMKK2
All Species:
12.42
Human Site:
S125
Identified Species:
30.37
UniProt:
Q96RR4
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96RR4
NP_006540.3
588
64732
S125
N
G
R
C
I
C
P
S
L
P
Y
S
P
V
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001093436
588
64878
S125
N
G
R
C
I
C
P
S
L
P
Y
S
P
V
G
Dog
Lupus familis
XP_543388
578
63709
V117
N
G
R
C
V
H
P
V
L
P
H
S
P
V
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8C078
588
64599
S125
N
G
R
C
I
C
P
S
L
S
Y
S
P
A
S
Rat
Rattus norvegicus
O88831
587
64428
S124
N
G
R
C
I
C
P
S
L
S
Y
S
P
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519677
851
91898
Y283
P
Y
W
T
P
L
V
Y
R
T
L
G
R
V
R
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001082316
523
58635
A111
N
L
A
Y
G
P
Y
A
T
G
P
A
S
H
I
Zebra Danio
Brachydanio rerio
NP_001014361
434
48727
G24
K
M
S
L
Q
E
R
G
T
Y
M
S
S
R
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9GN62
617
69630
L130
K
Q
Q
E
S
F
D
L
E
E
H
P
I
P
V
Sea Urchin
Strong. purpuratus
XP_785473
661
73509
E147
D
D
D
L
S
P
S
E
S
T
P
N
F
Q
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.4
92.1
N.A.
91.8
92.5
N.A.
38.6
N.A.
53.7
52.2
N.A.
N.A.
N.A.
21.5
44.7
Protein Similarity:
100
N.A.
98.8
93.8
N.A.
94.2
94.9
N.A.
50.5
N.A.
67.3
64.1
N.A.
N.A.
N.A.
40
58.4
P-Site Identity:
100
N.A.
93.3
66.6
N.A.
86.6
86.6
N.A.
6.6
N.A.
6.6
6.6
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
100
N.A.
93.3
80
N.A.
86.6
86.6
N.A.
6.6
N.A.
20
6.6
N.A.
N.A.
N.A.
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
10
0
0
0
10
0
20
0
% A
% Cys:
0
0
0
50
0
40
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
10
0
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
10
0
10
0
10
10
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
50
0
0
10
0
0
10
0
10
0
10
0
0
20
% G
% His:
0
0
0
0
0
10
0
0
0
0
20
0
0
10
0
% H
% Ile:
0
0
0
0
40
0
0
0
0
0
0
0
10
0
20
% I
% Lys:
20
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
0
20
0
10
0
10
50
0
10
0
0
0
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
60
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
10
0
0
0
10
20
50
0
0
30
20
10
50
10
0
% P
% Gln:
0
10
10
0
10
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
50
0
0
0
10
0
10
0
0
0
10
10
10
% R
% Ser:
0
0
10
0
20
0
10
40
10
20
0
60
20
0
40
% S
% Thr:
0
0
0
10
0
0
0
0
20
20
0
0
0
0
0
% T
% Val:
0
0
0
0
10
0
10
10
0
0
0
0
0
40
10
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
10
0
0
10
10
0
10
40
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _